The business and human rights agenda has continuously been expanding over the last few years. Still, many issues of this agenda remain underdeveloped. The special issue of Human Rights and International Legal Discourse would like to focus on one of those issues (which the Special Representative of the UN Secretary General on Business and Human Rights John Ruggie as well as the Institute for Business and Human Rights identified as one of the top 10 challenges): the human rights challenges posed by the activities and investments of multinational corporations in conflict zones.